Being Overweight and having a large waistline can increase the risk of developing aggressive prostate cancer, a study has found.
Researchers reveal that for every 10 cms increase in waist circumference, there is an increased chance of a man developing fatal prostate cancer by 18%. If a man has a high body mass index (BMI), the risk of being killed by a fatal strand of the disease also rises.
The study conducted by scientists at the University of Oxford examined on the association between the BMI and waist circumference and the increased risk of prostate cancer incidence, and a focus on tumor stage and grade and on mortality.
The researchers examined a total of 141,896 men with an average age of 52 Years from Eight European countries including Italy, Spain, Britain, the Netherlands, Greece, Germany, Sweden and Denmark. After 14 years, 7,022 cases of prostate cancer were observed among which 934 cases were fatal.
Researchers concentrated on cancers with a high grade and cancers which resulted in death. Men who have higher BMI and waist circumference were observed to have had an increased risk of high-grade prostate cancer, i.e. for every five kg/m2 increase 10% increased risk, and for every 10 cm Waist increase 13% increased cancer risks.
Also for every five kg/m2 increase in BMI, the increased risks of fatal prostate cancer are observed to be 14 percent, and for every 10 cm increase in waist circumference, the increased risk of fatal prostate cancer is observed to be 18 percent.
“The findings from this large prospective study show that the association between body size and prostate cancer is complex and varies by disease aggressiveness; men who have greater adiposity have an elevated risk of high-grade prostate cancer and death from prostate cancer”, the researchers added.
The study by Aurora Perez-Cornago and colleagues from the University of Oxford was presented at the European Obesity Summit in Gothenburg, Sweden.