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cervical cancer vaccine: India gets its first cervical cancer vaccine; women in their 30s remain vulnerable, must get regular check-ups done

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The victory over cervical cancer is one step closer.

Hours after India’s Comptroller General of Medicines approved the country’s first quadrivalent human papillomavirus (qHPV) vaccine against cervical cancer, Serum Institute of India (SII) CEO Adar Punawalla said his own qHPV development will be launched in end of this year.

A new vaccine to treat cervical cancer in women will be “affordable” according to the head of a biotech company.

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Indian HPV vaccine to be launched for the first time for cervical cancer in women, affordable and… https://t.co/g9uUubg2Bz

— Adar Poonawalla (@adarpoonawalla) 1657634534000

According to the World Health Organization (WHO), cervical cancer is the fourth most common cancer in women. In India, it is the second most common cancer among women aged 15 to 44.

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The National Health Portal of India (NHPI) reports that every year 122,844 women are diagnosed with cervical cancer and 67,477 die from the disease.

What causes cervical cancer?

Two types of human papillomavirus (HPV) (16 and 18) cause 70 percent of cervical cancers and precancerous lesions worldwide. An ICO HPV Information Center report states that about 82.7% of cases of invasive cervical cancer are due to 16 or 18 HPVs.

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Other types of HPV, also known as the most common viral infections of the genital tract, are known to cause sexually transmitted infections or diseases in men and women. The WHO states that most sexually active women and men will be infected with HPV at some point in their lives, and even more than once. However, over 90 percent of the infection is eventually cured. The problem can start when HPV infection is chronic in women and causes precancerous lesions leading to invasive cervical cancer.

Where does cervical cancer occur?
It all starts with changing the cylindrical shape of the tissue tube. Cervical cancer develops in women when cells grow uncontrollably in the cervix, the part that connects the uterus to the birth canal (vagina). Most cervical cancers occur at the junction of the endocervix (the upper two-thirds of the cervix from the uterus) and the ectocervix (the lower part of the cervix closest to the vagina).

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Although it can take 15 to 20 years for cervical cancer to develop, it may take 5 to 10 years for women with weakened immune systems to become infected. Importantly, according to WHO, women with HIV are six times more likely to develop cervical cancer than women without HIV.

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Can men get it?
The cervix is ​​the female organ of the reproductive system. Men biologically do not have a cervix. However, they do have a male version of the organ called the “prostatic uterus”, which is a sac-like depression at the back of the prostatic urethra.

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Look out for increased or unusual vaginal discharge, which can sometimes even be foul-smelling.

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Know the risk factors:
Sexual life from an early age

Having multiple sexual partners

Have many children

Long-term use (more than five years) of oral contraceptives

Smoke cigarettes

STDs or a weakened immune system

Warning signs
In the early stages, women with cervical cancer may experience irregular spotting or light bleeding between periods in women of reproductive age. For women who have gone through menopause, spotting and/or bleeding is common.

Women also need to be careful if they often experience pain during intercourse or bleeding after it. Look out for increased or unusual vaginal discharge, which can sometimes even be foul-smelling.

As the disease progresses, symptoms begin to worsen. Weight loss, fatigue, loss of appetite, vaginal discomfort with foul-smelling discharge, and difficulty urinating are some serious signs that women should look out for. Women also experience

pain in the back, leg, or pelvis, and swelling of the leg, or both, from the hip to the toes, and seek immediate medical attention. After advanced cancer metastasis, other serious symptoms may occur.

Precautions are better than cure
It is extremely important to get screened regularly for HPV and precancerous lesions, as the WHO states that cervical cancer can be cured with early diagnosis and treatment.

Women should be vaccinated against cervical cancer to prevent the disease. According to the WHO, girls between the ages of 9 and 14 should be vaccinated against HPV. For women over 30, regular screening, such as HPV DNA and HPV mRNA tests every 5 to 10 years, is vital. While HPV DNA testing detects high-risk HPV strains, HPV mRNA detects HPV infections leading to cellular transformation.

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In addition to the brand new qHPV SII vaccine, the WHO has so far approved four more vaccines that protect against HPV types 16 and 18. “The 9-valent vaccine protects against 5 additional oncogenic HPV types that cause an additional 20% of cervical cancers. vaccines also protect against HPV types 6 and 11, which cause anogenital warts.

Cervical cancer and other cancers can be caused by HPV infection. What you need to know

Cervical cancer and other cancers can be caused by HPV infection. What you need to know

Human papillomaviruses are a group of sexually transmitted viruses. High-risk HPVs can cause cancer.

What is HPV?

HPV (human papillomavirus) is a group of viruses. There are over 100 types of HPV, of which about 14 can cause cancer. They are also known as high risk types.

How can you get HPV?

HPV is a sexually transmitted infection. Most people become infected shortly after the onset of sexual activity.

How common is HPV?

According to the National Cancer Institute, almost all sexually active people become infected with HPV within a few months or a few years of starting sexual activity. About half of these infections are of the high-risk type.

Who is affected by HPV?

Both men and women can become infected with HPV and develop cancer caused by HPV.

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